Humulin®

This information is provided in response to your request. Resources may contain information about doses, uses, formulations and populations different from product labeling. See Prescribing Information above, if applicable.

Which syringe can be used with Humulin® R U-500 (insulin human) vial?

BD U-500 insulin syringe must be prescribed with Humulin R U-500 vial to avoid administration errors. Do not use any other type of syringe with Humulin R U-500 vial.

US_cFAQ_INS523_U500_SYRINGE_INFORMATION
US_cFAQ_INS523_U500_SYRINGE_INFORMATION
en-US

Syringe Information

BD™ U-500 Insulin Syringe

BD (Becton, Dickinson and Company) U-500 insulin syringe must be prescribed with Humulin® R U-500 (insulin human injection) 500 units/mL (U‑500R) vial to avoid administration errors. Do not use any other type of syringe with U‑500R vial.1 

BD U-500 insulin syringe is a 0.5 mL syringe that features

  • a U-500 symbol (green)
  • a green needle shield
  • a gray syringe plunger
  • dosing up to 250 units per injection
  • numerical markings from 25 to 250 units
  • dosing increments of 5 units per syringe dose line, and
  • 6-mm, 31-gauge needle.1-3

BD U-500 insulin syringe requires a separate prescription (Sample Prescription for BD U-500 insulin syringe), and no other syringe can be substituted.1,4

Sample Prescription for BD U-500 insulin syringe4

Figure 1 description: Sample prescription for BD U-500 insulin syringe specifies that the patient using the U-500 vial must be prescribed BD U‑500 insulin syringe only.

Abbreviation: U-500 = Humulin® R U-500 (insulin human injection) 500 units/mL.

Humulin R U-500 Vial

The U‑500R vial is a 20 mL multiple dose vial (10,000 units per vial) that features

  • a band of aqua coloring on vial and vial packaging
  • a green “U-500” concentration statement
  • a green protective cap
  • a red warning on the front panel, and
  • a statement advising use with only BD U-500 insulin syringe.1,2,4

BD U-500 insulin syringe does not require dose conversion; the dose lines on BD U-500 insulin syringe show the number of units of U‑500R to be injected. Each marking on BD U-500 insulin syringe represents 5 units of insulin.1

Additional information regarding BD U-500 insulin syringe may be obtained by contacting BD at

References

1Humulin R U-500 [package insert]. Indianapolis, IN: Eli Lilly and Company; 2019.

2Humulin R U-500 Vial [instructions for use]. Indianapolis, IN: Eli Lilly and Company; 2019.

3BD™ U-500 Insulin Syringes 6mm x 31G 1/2 mL/cc. BD. Accessed April 25, 2022. https://www.bd.com/en-us/products-and-solutions/products/product-page.326730

4Data on file, Eli Lilly and Company and/or one of its subsidiaries.

5Customer portals and quick links. BD. Accessed April 25, 2022. https://www.bd.com/en-us/support

Date of Last Review: April 22, 2022


Contact Lilly

Call Us

If you need information about a Lilly product or want to report an Adverse Event or Product Complaint, you may call us.

Available Mon – Friday, 9am-7pm (EST), excluding holidays

Or you can

Chat with us

Chat with us

Submit a Request

Visit Us @LillyMedical