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There is no information on the use of tirzepatide in patients with hepatitis because patients were excluded from tirzepatide clinical trials if they had acute or chronic hepatitis, signs and symptoms of any liver disease other than NAFLD, or ALT ≤3.0 times the ULN. Patients with NAFLD were eligible to participate in this trial if their ALT was ≤3.0 times the ULN.
ALT = alanine aminotransferase
NAFLD = nonalcoholic fatty liver disease
ULN = upper limit of normal
Date of Last Review: March 19, 2021