Mounjaro™ (tirzepatide) injection

2.5 mg/5 mg/7.5 mg/10 mg/12.5 mg/15 mg

This information is provided in response to your request. Resources may contain information about doses, uses, formulations and populations different from product labeling. See Prescribing Information above, if applicable.

Tirzepatide: Comparison With Once-Weekly Semaglutide 2 mg

Tirzepatide compared with semaglutide 2 mg has not been studied.


Detailed Information

SURPASS-2 compared tirzepatide with once-weekly semaglutide 1 mg, the highest approved dose of semaglutide available at the time.1,2

Lilly has not conducted and are not currently conducting clinical studies comparing tirzepatide with once-weekly semaglutide 2 mg.2


1A study of tirzepatide (LY3298176) versus semaglutide once weekly as add-on therapy to metformin in participants with type 2 diabetes (SURPASS-2). identifier: NCT03987919. Updated March 11, 2021. Accessed March 23, 2021.

2Data on file, Eli Lilly and Company and/or one of its subsidiaries.


Lilly = Eli Lilly and Company

Date of Last Review: March 23, 2021

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