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Reyvow ® (lasmiditan) tablets CV50 mg, 100 mg
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Lasmiditan was eliminated with a geometric mean t½ value of approximately 5.7 hours.1
No accumulation of lasmiditan was observed with daily dosing.1
Lasmiditan is primarily metabolized by ketone reduction to the alcohol S-M8, with very little parent drug (approximately 3%) excreted unchanged in urine.1
Renal excretion is a minor route of lasmiditan clearance.1
1Reyvow [package insert]. Indianapolis, IN: Eli Lilly and Company; 2021.
PK = pharmacokinetics
t1/2 = elimination half-life
Date of Last Review: November 20, 2018