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Humalog® Therapies
Humalog® U-100 (insulin lispro injection)
100 units/mLHumalog® U-200 (insulin lispro injection)
200 units/mLHumalog® MIX50/50™ (50% insulin lispro protamine suspension 50% insulin lispro injection [rDNA origin])
100 units/mLHumalog® MIX75/25™ (75% insulin lispro protamine suspension 25% insulin lispro injection [rDNA origin])
100 units/mLThis information is provided in response to your request. Resources may contain information about doses, uses, formulations and populations different from product labeling. See Prescribing Information above, if applicable.
What is the difference between Insulin Lispro 100 units/mL and Humalog® (insulin lispro) 100 units/mL?
When transitioning from Humalog® (insulin lispro) 100 units/mL to Insulin Lispro 100 units/mL, no dose conversion is needed.
Detailed Information
Insulin Lispro 100 units/mL is an unbranded biologic of Humalog® (insulin lispro injection) 100 units/mL.1
An unbranded biologic is not different from the brand name drug in its
- route of administration
- dosage form
- strength, or
- presentation.2
Unbranded Insulin Lispro 100 units/mL products are identical to branded Humalog 100 units/mL products in terms of
- active ingredients
- inactive ingredients, and
- manufacturing facilities, and
- packaging facilities.1
Unbranded Insulin Lispro presentations have unique NDC (National Drug Code) numbers, labels, and package inserts.1
Do not perform dose conversion when transitioning to the unbranded Insulin Lispro 100 units/mL from Humalog 100 units/mL, or vice versa.3,4
For example, if a patient is transitioning from 20 units of Humalog 100 units/mL, the patient would administer 20 units of unbranded Insulin Lispro injection 100 units/mL.
Enclosed Prescribing Information
References
1Data on file, Eli Lilly and Company and/or one of its subsidiaries.
2US Food and Drug Administration (FDA). Purple Book Database of Licensed Biological Products: FAQs. Accessed December 06, 2021. https://purplebooksearch.fda.gov/faqs#9
3Humalog [package insert]. Indianapolis, IN: Eli Lilly and Company; 2019.
4Insulin Lispro Injection [package insert]. Indianapolis, IN: Eli Lilly and Company; 2020.
Date of Last Review: April 12, 2022