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Humulin® Therapies
Humulin® R (U-100) (regular insulin human injection, USP [rDNA origin])
100 units/mLHumulin® R (U-500) (regular U-500 [concentrated] insulin human injection, USP [rDNA origin])
500 units/mLHumulin® 70/30 (70% human insulin isophane suspension and 30% human insulin injection [rDNA origin])
100 units/mLHumulin® N U-100 (human insulin [rDNA origin] isophane suspension)
100 units/mLThis information is provided in response to your request. Resources may contain information about doses, uses, formulations and populations different from product labeling. See Prescribing Information above, if applicable.
HUMULIN insulin: Aseptic Techniques During Supply Shortages
During medical supply shortages, Lilly encourages patients to contact their health care provider for assistance.
Patients should follow the guidance on good aseptic techniques, such as handwashing and use of alcohol swabs, as outlined in the Humulin insulin “Instructions for Use.”1-3
Guidance During Medical Supply Shortages
The COVID-19 pandemic has caused widespread medical supply shortages, including alcohol swabs and bottles of 70% isopropyl alcohol.
During shortages, patients should contact their health care provider for suggested alternative aseptic measures.
Injection Site Preparation
As an alternative to the use of alcohol, the WHO recommends the use of soap and water for skin preparation and disinfection of injection sites.4
Pen Preparation
There is a low risk to patient safety if the cartridge septum is not swabbed with alcohol prior to attaching a new Pen needle. Do not use other cleaners, such as bleach, to sanitize the cartridge septum as it may damage the Pen. Do not submerge the Pen in any fluid as this may damage the device and label.5
Enclosed Prescribing Information
HUMULIN® N (isophane insulin human suspension), for subcutaneous use, Lilly
HUMULIN® R U-100 (insulin human injection), for subcutaneous or intravenous use, Lilly
HUMULIN® R U-500 (insulin human injection), for subcutaneous use, Lilly
1. Humulin R U-500 KwikPen [instructions for use]. Indianapolis, IN: Eli Lilly and Company; 2019.
2. Humulin N U-100 KwikPen [instructions for use]. Indianapolis, IN: Eli Lilly and Company; 2019.
3. Humulin 70/30 U-100 KwikPen [instructions for use]. Indianapolis, IN: Eli Lilly and Company; 2019.
4. World Health Organization. WHO best practices for injections and related procedures toolkit. Published March 2010. Accessed March 23, 2020. https://apps.who.int/iris/bitstream/handle/10665/44298/9789241599252_eng.pdf?sequence=1
5. Data on file, Eli Lilly and Company and/or one of its subsidiaries.
Glossary
COVID-19 = coronavirus disease 2019
Lilly = Eli Lilly and Company
Pen = KwikPen®
WHO = World Health Organization
Date of Last Review: March 23, 2020