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Humalog®
Humalog® U-100 (insulin lispro injection)
100 units/mLHumalog® U-200 (insulin lispro injection)
200 units/mLHumalog® MIX50/50™ (50% insulin lispro protamine suspension 50% insulin lispro injection [rDNA origin])
100 units/mLHumalog® MIX75/25™ (75% insulin lispro protamine suspension 25% insulin lispro injection [rDNA origin])
100 units/mLThis information is provided in response to your request. Resources may contain information about doses, uses, formulations and populations different from product labeling. See Prescribing Information above, if applicable.
Patients should follow the guidance on good aseptic techniques, such as handwashing and use of alcohol swabs, as outlined in the Humalog insulin “Instructions for Use.”1-5
Guidance During Medical Supply Shortages
The COVID-19 pandemic has caused widespread medical supply shortages, including alcohol swabs and bottles of 70% isopropyl alcohol.
During shortages, patients should contact their health care provider for suggested alternative aseptic measures.
Injection Site Preparation
As an alternative to the use of alcohol, the WHO recommends the use of soap and water for skin preparation and disinfection of injection sites.6
Pen Preparation
There is a low risk to patient safety if the cartridge septum is not swabbed with alcohol prior to attaching a new Pen needle. Do not use other cleaners, such as bleach, to sanitize the cartridge septum as it may damage the Pen. Do not submerge the Pen in any fluid as this may damage the device and label.7
Enclosed Prescribing Information
HUMALOG® (insulin lispro injection), for subcutaneous or intravenous use, Lilly
HUMALOG® Mix75/25™ (insulin lispro protamine and insulin lispro injectable suspension), for subcutaneous use, Lilly
1. Humalog 100 units/mL KwikPen [instructions for use]. Indianapolis, IN: Eli Lilly and Company; 2019.
2. Humalog 100 units/mL Junior KwikPen [instructions for use]. Indianapolis, IN: Eli Lilly and Company; 2019.
3. Humalog 200 units/mL KwikPen [instructions for use]. Indianapolis, IN: Eli Lilly and Company; 2019.
4. Humalog Mix50/50 KwikPen [instructions for use]. Indianapolis, IN: Eli Lilly and Company; 2019.
5. Humalog Mix75/25 KwikPen [instructions for use]. Indianapolis, IN: Eli Lilly and Company; 2019.
6. World Health Organization. WHO best practices for injections and related procedures toolkit. Published March 2010. Accessed March 23, 2020. https://apps.who.int/iris/bitstream/handle/10665/44298/9789241599252_eng.pdf?sequence=1
7. Data on file, Eli Lilly and Company and/or one of its subsidiaries.
Glossary
COVID-19 = coronavirus disease 2019
Lilly = Eli Lilly and Company
Pen = KwikPen®
WHO = World Health Organization
Date of Last Review: March 23, 2020
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