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Cialis ® (tadalafil) tablets
2.5 mg, 5 mg, 10mg, 20 mg tablets
This information is provided in response to your request. Resources may contain information about doses, uses, formulations and populations different from product labeling. See Prescribing Information above, if applicable.
CIALIS® (tadalafil): Hepatic Impairment and Liver Function
Caution should be exercised when prescribing CIALIS to patients with severe hepatic impairment.
Dosing With Hepatic Impairment
Tadalafil use in patients with hepatic impairment for treatment of ED, BPH, and ED/BPH is seen in Table 1 and Table 2.
Table 1. Tadalafil Dosing and Administration for Erectile Dysfunction in Patients With Hepatic Impairment1
|
Dosing and Administration |
Tadalafil for Use as Needed |
Tadalafil for Once-Daily Use |
|
Hepatic impairment (mild to moderate)a |
Not to exceed 10 mg once per day. The use of tadalafil once per day has not been extensively evaluated; caution advised if prescribed. |
The use of tadalafil once per day has not been extensively evaluated; caution advised if prescribed. |
|
Hepatic impairment (severe)a |
Use is NOT recommended. |
Use is NOT recommended. |
a Hepatic impairment: mild or moderate=Child-Pugh class A or B; severe=Child-Pugh class C.
Table 2. Tadalafil Dosing and Administration for Benign Prostatic Hyperplasia and for Erectile Dysfunction and Benign Prostatic Hyperplasia1
|
Dosing and Administration |
Tadalafil for BPH |
Tadalafil for ED and BPH |
|
Hepatic impairment (mild to moderate)a |
The use of tadalafil once per day has not been extensively evaluated; caution advised if prescribed. |
The use of tadalafil once per day has not been extensively evaluated; caution advised if prescribed. |
|
Hepatic impairment (severe)a |
Use is NOT recommended. |
Use is NOT recommended. |
Abbreviations: BPH = benign prostatic hyperplasia; ED = erectile dysfunction.
a Hepatic impairment: mild or moderate=Child-Pugh class A or B; severe=Child-Pugh class C.
Enclosed Prescribing Information
CIALIS® (tadalafil) tablets, for oral use, Lilly
1. Cialis [package insert]. Indianapolis, IN: Eli Lilly and Company; 2018.
Glossary
BPH = benign prostatic hyperplasia
ED = erectile dysfunction
Date of Last Review: July 09, 2020